There's a whole subforum full of tips, unless Titanquest.net is not loading once again. :p
The synergies are not the same. The whole Mod is inspired by D2 rather than trying to recreate every bit exactly the same way.
Skills have (mostly visible) skill modifiers in TQ instead. That is why Leap Attack does not show as a skill on its own - it is an extension of Leap.
Vio
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Cosmic unlikeliness, errant human being, leisure time actor, studied molecular scientist and aspiring game designer.